Pepteca

Cognitive & mood

Selank

Tuftsin analog · 7-aa · anxiolytic

Semax's calmer sibling — a Russian anxiolytic peptide used for anxiety and mood, with the same 'clinical there, research-only here' caveat.

Reference status

Editorial research · independent review pending · 3 claims graded

Editorial researchResearch-onlyEmerging · early human71% positive discussion

What it is

Selank is a synthetic analog of the immune peptide tuftsin, developed in Russia as an anti-anxiety agent. It is often described as the calming counterpart to Semax's stimulation, and the two are frequently used together.

Like Semax, it has Russian clinical history but little independently verifiable Western trial data. It is used as a nootropic/anxiolytic, typically via nasal spray.

The science, graded

What’s claimed — and how strong the evidence behind each claim actually is.

“Reduces anxiety without sedation”

Supported by Russian clinical use and small studies; limited independent replication.

Claim-level citation mapping is in progress.

emerging
Emerging · early human

“Improves mood and stress resilience”

Commonly reported by users; not established in large Western trials.

Claim-level citation mapping is in progress.

anecdotal
Anecdotal · community

“Non-addictive alternative to benzodiazepines”

Mechanistically plausible and promising, but not a proven clinical substitute.

Claim-level citation mapping is in progress.

preclinical
Preclinical · animal only

Legal and regulatory context

Separate summaries for Great Britain, the United States, and the European Union. These are preliminary research summaries awaiting independent regional review; they are not legal determinations or advice.

Great Britain

Preliminary researchResearch-only

Not a licensed medicine in the UK; research-only here. No legal human-use supplement route.

This is preliminary regulatory research, not a reviewed legal determination or legal advice.

United States

Preliminary researchReview pending

Regional legal and regulatory review required before publication.

This is preliminary regulatory research, not a reviewed legal determination or legal advice.

European Union

Preliminary researchReview pending

Regional legal and regulatory review required before publication.

This is preliminary regulatory research, not a reviewed legal determination or legal advice.

What the community says

Well-regarded in nootropics circles for taking the edge off anxiety, especially stacked with Semax. Reports are generally positive but effect sizes described as subtle.

Share of positive discussion71%

Where they’re talking

  • r/NootropicsAnxiety and Semax-pairing threads.
  • r/PeptidesNasal-spray dosing discussion.

References

  1. 1.Supply unlicensed medicinal products (specials) · MHRA
  2. 2.FDA's Concerns About Unapproved Drugs · U.S. Food and Drug Administration
  3. 3.Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks · U.S. Food and Drug Administration
  4. 4.Buying medicines online · European Medicines Agency
Educational, not advice or endorsement. Educational reference only. Independent review is pending. Do not use this entry to make medical, purchasing, dosing, or treatment decisions.This editorial research entry preserves the existing material but has not yet passed independent scientific and regional regulatory review.