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18rem}.lg\:grid-cols-\[minmax\(0\,1fr\)_25rem\]{grid-template-columns:minmax(0,1fr) 25rem}.lg\:grid-cols-\[minmax\(0\,1fr\)_minmax\(17rem\,25rem\)\]{grid-template-columns:minmax(0,1fr) minmax(17rem,25rem)}.lg\:items-center{align-items:center}.lg\:items-end{align-items:flex-end}.lg\:items-start{align-items:flex-start}.lg\:gap-12{gap:calc(var(--spacing) * 12)}.lg\:gap-16{gap:calc(var(--spacing) * 16)}.lg\:border-t{border-top-style:var(--tw-border-style);border-top-width:1px}.lg\:border-r{border-right-style:var(--tw-border-style);border-right-width:1px}.lg\:border-b-0{border-bottom-style:var(--tw-border-style);border-bottom-width:0}.lg\:border-l-0{border-left-style:var(--tw-border-style);border-left-width:0}.lg\:px-0{padding-inline:0}.lg\:pt-8{padding-top:calc(var(--spacing) * 8)}.lg\:pb-1{padding-bottom:var(--spacing)}.lg\:pb-12{padding-bottom:calc(var(--spacing) * 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0px 0px 0px 1px;--shadow-subtle:#33363c0d 0px 1px 2px 0px, #33363c0d 0px 0px 0px 1px;--shadow-subtle-2:#33363c0f 0px 0px 0px 1px;--shadow-float:#17191c2e 0px 30px 60px -20px, #17191c1f 0px 12px 24px -12px;--shadow-subtle-3:var(--shadow-float);--shadow-cell:var(--shadow-subtle);--glow-lumen:none;--ease-fluid:cubic-bezier(.22, 1, .36, 1);--ease-swim:cubic-bezier(.4, 0, .2, 1);--font-body:var(--font-quicksand), ui-sans-serif, system-ui, sans-serif;--font-display:var(--font-comfortaa), var(--font-quicksand), ui-sans-serif, system-ui, sans-serif;--font-serif:var(--font-comfortaa), ui-sans-serif, sans-serif;--font-data:var(--font-plex-mono), ui-monospace, SFMono-Regular, Menlo, monospace;--rail-w:88px;--wrap:1240px;--section-space:clamp(52px, 7vw, 88px);--lightningcss-light:initial;--lightningcss-dark: ;color-scheme:light}*{border-color:var(--line)}html{scroll-behavior:smooth;-webkit-text-size-adjust:100%}body{background:var(--paper-warm);color:var(--body);font-family:var(--font-body);-webkit-font-smoothing:antialiased;text-rendering:optimizelegibility;font-size:14.5px;font-weight:500;line-height:1.6;overflow-x:hidden}::selection{background:var(--hover-fill);color:var(--ink)}:focus-visible{outline:2px solid var(--ink);outline-offset:2px;border-radius:4px}.skip-link{z-index:100;border-radius:var(--r-md);background:var(--ink);color:var(--paper);transition:transform .16s var(--ease-fluid);padding:.7rem 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h3{font-family:var(--font-display);color:var(--ink);margin:1.5em 0 .4em;font-size:16px;font-weight:700}.prose-bio a{color:var(--ink);text-underline-offset:3px;text-decoration:underline;text-decoration-thickness:1px}.prose-bio strong{color:var(--ink);font-weight:700}.content-gate{border:1px solid var(--line-strong);border-radius:var(--r-xl);background:var(--paper);position:relative}@supports (color:color-mix(in lab, red, red)){.content-gate{background:color-mix(in oklab, var(--paper) 96%, var(--panel))}}.content-gate{box-shadow:var(--shadow-subtle);padding:clamp(1.4rem,4vw,2.25rem)}.gated-content{position:relative}.gated-content--locked{min-height:31rem;margin-top:1.25rem;overflow:hidden}.gated-content--locked .gated-content__body{filter:blur(3px);-webkit-user-select:none;user-select:none;opacity:.32;pointer-events:none;max-height:22rem;overflow:hidden}.gated-content--locked:after{content:"";background:linear-gradient(to bottom, transparent 0%, var(--paper-warm) 90%);pointer-events:none;height:25rem;position:absolute;inset:0 0 auto}.gated-content__prompt{z-index:1;position:absolute;inset:9rem 0 auto}.prose-bio ul{margin:0 0 1.05em;padding-left:0;list-style:none}.prose-bio li{margin:.45em 0;padding-left:1.4em;position:relative}.prose-bio li:before{content:"";background:var(--ghosted);border-radius:9999px;width:6px;height:6px;position:absolute;top:.62em;left:.15em}.panel{background:var(--paper);border:1px solid var(--line);border-radius:var(--radius-cards);position:relative}.panel-float{background:var(--paper);border-radius:var(--r-md);box-shadow:var(--shadow-float)}.glass{background:var(--paper)}@supports (color:color-mix(in lab, red, red)){.glass{background:color-mix(in oklab, var(--paper) 88%, transparent)}}.glass{-webkit-backdrop-filter:blur(10px)}.glassbar{-webkit-backdrop-filter:blur(10px)saturate(1.05);color:#fff;background:#1c1e224d;border:1px solid #ffffff47}.cell-shape,.cell-shape-2{border-radius:var(--r-md)}.reactive{transition:background .2s var(--ease-fluid), border-color .2s var(--ease-fluid), transform .2s var(--ease-fluid), box-shadow .2s var(--ease-fluid)}.reactive:hover{background:var(--paper);border-color:var(--line-strong);box-shadow:var(--shadow-subtle);transform:translateY(-2px)}.reactive:active{transform:translateY(0)scale(.99)}.nucleus{border-radius:var(--r-md);background:var(--paper);border:1px solid var(--line);color:var(--ink);place-items:center;display:grid}.btn{font-family:var(--font-body);letter-spacing:.01em;border-radius:var(--r-lg);transition:all .18s var(--ease-fluid);cursor:pointer;white-space:nowrap;justify-content:center;align-items:center;gap:.5rem;min-height:44px;padding:10px 18px;font-size:13.5px;font-weight:700;display:inline-flex}.btn-lumen{color:#fff;background:var(--ink);border:1px solid var(--ink)}.btn-lumen:hover{background:var(--lumen-deep)}.btn:active{transform:translateY(1px)scale(.99)}.btn-ghost{color:var(--ink);background:var(--paper);border:1px solid var(--line-strong)}.btn-ghost:hover{background:var(--panel)}.badge{font-family:var(--font-body);letter-spacing:.02em;border-radius:var(--radius-badges);border:1px solid var(--line);background:var(--panel-2);color:var(--ink-soft);align-items:center;gap:.4rem;padding:3px 10px;font-size:11px;font-weight:700;display:inline-flex}.grade{font-family:var(--font-body);letter-spacing:.05em;text-transform:uppercase;border-radius:var(--radius-badges);border:1px solid var(--line);background:var(--panel);color:var(--body);align-items:center;gap:.45rem;padding:3px 10px 3px 8px;font-size:10.5px;font-weight:700;display:inline-flex}.grade:before{content:"";background:var(--g);border-radius:2px;width:7px;height:7px}.grade-strong{--g:var(--grade-strong);color:var(--grade-strong)}.grade-emerging{--g:var(--grade-emerging)}.grade-preclinical{--g:var(--grade-preclinical)}.grade-anecdotal{--g:var(--grade-anecdotal)}.grade-hype{--g:var(--grade-hype)}.lane{font-family:var(--font-body);letter-spacing:.04em;border-radius:var(--radius-badges);border:1px solid var(--line);background:var(--panel);color:var(--l);align-items:center;gap:.4rem;padding:3px 10px;font-size:10.5px;font-weight:700;display:inline-flex}.lane:before{content:"";background:var(--l);border-radius:9999px;width:6px;height:6px}.lane-cosmetic{--l:var(--lane-cosmetic)}.lane-rx{--l:var(--lane-rx)}.lane-research{--l:var(--lane-research)}.lane-restricted{--l:var(--lane-restricted)}.meter{background:var(--hover-fill);border-radius:9999px;height:4px;overflow:hidden}.meter>span{background:var(--ink);border-radius:9999px;height:100%;display:block}.rating{gap:3px;display:inline-flex}.rating>i{background:var(--hover-fill);border-radius:2px;width:13px;height:5px;display:block}.rating>i.on{background:var(--g,var(--ink))}.strand,.strand-dotted{background:var(--line);height:1px}.text-glow{text-shadow:none}.tabular{font-variant-numeric:tabular-nums}.caption{font-family:var(--font-body);color:var(--faint);font-size:11.5px;font-weight:600}.field{background:var(--paper);border:1px solid var(--line-strong);border-radius:var(--radius-inputs);min-height:44px;font-family:var(--font-body);color:var(--ink);padding:10px 13px;font-size:14px;font-weight:500;transition:border-color .15s,box-shadow .15s}.field::placeholder{color:var(--ghosted)}.field:focus{border-color:var(--ink);box-shadow:0 0 0 3px var(--hover-fill);outline:none}.announce{background:var(--panel);color:var(--ink);font-size:13px}.hero-photo{background:radial-gradient(52% 68% at 82% 30%,#de8a4280,#0000 62%),radial-gradient(46% 60% at 66% 62%,#c174326b,#0000 60%),radial-gradient(70% 90% at 12% 18%,#ffffff29,#0000 55%),radial-gradient(60% 60% at 30% 80%,#ffffff1a,#0000 60%),linear-gradient(108deg,#565b63 0%,#454a52 38%,#34383f 72%,#2b2f36 100%);position:relative;overflow:hidden}.hero-photo:after{content:"";pointer-events:none;background:linear-gradient(#ffffff1f,#0000 30%),radial-gradient(80% 30% at 40% 46%,#ffffff24,#0000 70%),radial-gradient(90% 24% at 60% 78%,#ffffff1a,#0000 70%);position:absolute;inset:0}.hero-wash{pointer-events:none;background:0 0;position:absolute;inset:0}.ruled-label{align-items:center;gap:12px;display:flex}.ruled-label:after{content:"";background:var(--line);flex:1;height:1px}@keyframes rise{0%{transform:translateY(8px)}to{transform:translateY(0)}}.breathe,.drift,.drift-slow,.morph{animation:none}.reveal{opacity:1;transform:none}.rise{animation:rise .5s var(--ease-fluid) both}@media (prefers-reduced-motion:reduce){*,:before,:after{scroll-behavior:auto!important;transition-duration:.001ms!important;animation-duration:.001ms!important;animation-iteration-count:1!important;animation-delay:0s!important}.reveal{opacity:1;transform:none}.rise{opacity:1;transform:none;animation:none!important}}.wrap{width:100%;max-width:var(--wrap);margin-inline:auto;padding-inline:28px}.wrap-narrow{width:100%;max-width:720px;margin-inline:auto;padding-inline:28px}.page-intro{padding-block:clamp(42px,7vw,82px) clamp(34px,5vw,58px)}.page-kicker{color:var(--faint);align-items:center;gap:14px;display:flex}.page-kicker:after{content:"";background:var(--line-strong);width:min(180px,30vw);height:1px}.section-heading{border-bottom:1px solid var(--line);justify-content:space-between;align-items:flex-end;gap:24px;padding-bottom:14px;display:flex}.editorial-surface{background:radial-gradient(70% 80% at 88% 12%,#c4885224,#0000 58%),radial-gradient(70% 60% at 10% 88%,#6f858d1f,#0000 60%),linear-gradient(145deg,#fcfbf8 0%,#f2f0eb 60%,#e8e7e2 100%)}.control-surface{background:var(--paper)}@supports (color:color-mix(in lab, red, red)){.control-surface{background:color-mix(in oklab, var(--paper) 92%, transparent)}}.control-surface{border:1px solid var(--line);box-shadow:var(--shadow-subtle)}.library-view-auto .view-cards{background:var(--paper)!important;color:var(--ink)!important;box-shadow:var(--shadow-subtle-2)!important}@media (min-width:768px){.library-view-auto .view-cards{color:var(--faint)!important;box-shadow:none!important;background:0 0!important}.library-view-auto .view-table{background:var(--paper)!important;color:var(--ink)!important;box-shadow:var(--shadow-subtle-2)!important}}.quiet-link{color:var(--ink);align-items:center;gap:7px;font-size:13px;font-weight:700;text-decoration:none;display:inline-flex}.quiet-link:hover{text-underline-offset:4px;text-decoration:underline}.reference-aside{border-top:2px solid var(--ink);background:var(--paper);border-radius:0 0 var(--r-xl) var(--r-xl);box-shadow:var(--shadow-subtle)}@media (max-width:639px){.wrap,.wrap-narrow{padding-inline:20px}.page-intro{padding-top:40px}}.hide-scrollbar::-webkit-scrollbar{display:none}.hide-scrollbar{scrollbar-width:none}@property --tw-translate-x{syntax:"*";inherits:false;initial-value:0}@property --tw-translate-y{syntax:"*";inherits:false;initial-value:0}@property --tw-translate-z{syntax:"*";inherits:false;initial-value:0}@property --tw-rotate-x{syntax:"*";inherits:false}@property --tw-rotate-y{syntax:"*";inherits:false}@property --tw-rotate-z{syntax:"*";inherits:false}@property --tw-skew-x{syntax:"*";inherits:false}@property --tw-skew-y{syntax:"*";inherits:false}@property --tw-divide-y-reverse{syntax:"*";inherits:false;initial-value:0}@property --tw-border-style{syntax:"*";inherits:false;initial-value:solid}@property --tw-leading{syntax:"*";inherits:false}@property --tw-font-weight{syntax:"*";inherits:false}@property --tw-tracking{syntax:"*";inherits:false}@property --tw-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-shadow-color{syntax:"*";inherits:false}@property --tw-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-inset-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-inset-shadow-color{syntax:"*";inherits:false}@property --tw-inset-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-ring-color{syntax:"*";inherits:false}@property --tw-ring-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-inset-ring-color{syntax:"*";inherits:false}@property --tw-inset-ring-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-ring-inset{syntax:"*";inherits:false}@property --tw-ring-offset-width{syntax:"<length>";inherits:false;initial-value:0}@property --tw-ring-offset-color{syntax:"*";inherits:false;initial-value:#fff}@property --tw-ring-offset-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-blur{syntax:"*";inherits:false}@property --tw-brightness{syntax:"*";inherits:false}@property --tw-contrast{syntax:"*";inherits:false}@property --tw-grayscale{syntax:"*";inherits:false}@property --tw-hue-rotate{syntax:"*";inherits:false}@property --tw-invert{syntax:"*";inherits:false}@property --tw-opacity{syntax:"*";inherits:false}@property --tw-saturate{syntax:"*";inherits:false}@property --tw-sepia{syntax:"*";inherits:false}@property --tw-drop-shadow{syntax:"*";inherits:false}@property --tw-drop-shadow-color{syntax:"*";inherits:false}@property --tw-drop-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-drop-shadow-size{syntax:"*";inherits:false}@property --tw-backdrop-blur{syntax:"*";inherits:false}@property --tw-backdrop-brightness{syntax:"*";inherits:false}@property --tw-backdrop-contrast{syntax:"*";inherits:false}@property --tw-backdrop-grayscale{syntax:"*";inherits:false}@property --tw-backdrop-hue-rotate{syntax:"*";inherits:false}@property --tw-backdrop-invert{syntax:"*";inherits:false}@property --tw-backdrop-opacity{syntax:"*";inherits:false}@property --tw-backdrop-saturate{syntax:"*";inherits:false}@property --tw-backdrop-sepia{syntax:"*";inherits:false}@property --tw-scale-x{syntax:"*";inherits:false;initial-value:1}@property --tw-scale-y{syntax:"*";inherits:false;initial-value:1}@property --tw-scale-z{syntax:"*";inherits:false;initial-value:1}@keyframes pulse{50%{opacity:.5}}